Jeremy Lin seems like he might be the real deal. Tom Brady and Albert Pujols come to mind. I passed on buying the 2001 Bowman Chrome Auto redemption at $300 and that card sells for $4,000 easily today.
Brett Lawrie is doing that right now.
His base Bowman Chrome Auto RC came out at about $70 and it has gone completely insane since November. Below is a small snapshot of the price differences:
Base Bowman Chrome Autograph - From: $70 To: $250
Blue Refractor Auto - From: $150 To: $450
Gold Refractor Auto - From: $500 To: $650-$800
It also helps that his card has been deemed an SSP and the hype around his 2012 season is over and above most players.