Goalies are much too fungible in my mind for them to be compared to the top skaters in the game. The one exception would Bobrovsky. He has been lights out for a season and a half now. I wouldn't consider a forward that isn't great in the defensive zone, so I wouldn't look to guys like Gaudreau, Kane, or Ovechkin. Malkin is up around the top-5, Matthews top-10ish, Doughty, Subban, Hedman are in that top-10 mix too. For me Kucherov is the one that I waffle back and forth on for number 3.
Karlsson is the best offensive d-man by a lot. And he is right there with Doughty, Subban, Hedman for their defensive play. The biggest thing for me though, is that he makes his partner look a lot better, whether it be Methot, Oduya. When I watch him play I am reminded of Chris Pronger's time in Edmonton with Marc-Andre Bergeron. Giordano, also is like this. Just look at Brodie with/without him, same goes for Hamilton.